Important Precautions- Why Serum Separator Tubes Should Not Be Collected Improperly

by liuqiyue

A serum separator tube should not be collected for blood tests that require a specific collection method. These tubes are designed for collecting serum, which is the liquid portion of blood that remains after the blood cells have been separated. However, certain tests require plasma, the liquid that remains after the blood cells and serum have been removed. Using a serum separator tube for these tests can lead to inaccurate results and potentially harmful consequences for the patient.

The primary purpose of a serum separator tube is to allow for the separation of serum from the blood cells. This is achieved by adding an anticoagulant, such as sodium heparin or EDTA, to the blood sample. The anticoagulant prevents the blood from clotting and allows for the separation of the serum and cells. Once the tube is filled, it is inverted several times to ensure proper mixing of the anticoagulant with the blood.

However, some blood tests require plasma rather than serum. Plasma is the liquid that remains after the blood cells and serum have been removed, and it contains important components such as clotting factors and proteins. When a serum separator tube is used for these tests, the anticoagulant can interfere with the test results, leading to inaccurate readings.

For example, coagulation studies, such as the PT (prothrombin time) and APTT (activated partial thromboplastin time), require plasma to accurately measure the clotting time of the blood. If a serum separator tube is used instead, the anticoagulant can affect the clotting factors and proteins in the plasma, resulting in incorrect measurements.

In addition to coagulation studies, other tests that require plasma include those measuring certain enzymes, hormones, and electrolytes. Using a serum separator tube for these tests can lead to inaccurate results, which may cause misdiagnosis or improper treatment of the patient.

To avoid these issues, it is crucial to use the appropriate collection tube for each blood test. If a serum separator tube is not specified, it is best to consult with a healthcare professional or refer to the laboratory’s guidelines to determine the correct collection method. In some cases, a plain red top tube or a lithium heparin tube may be more suitable for the test.

In conclusion, a serum separator tube should not be collected for blood tests that require plasma. Using the wrong tube can lead to inaccurate results and potentially harmful consequences for the patient. It is essential to use the appropriate collection tube for each test to ensure accurate and reliable results.

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